InnerOrigin is excited to introduce Conceiveplease products to our platform! Read about their amazing and natural pregnancy planning kits and how they work!

• This article was provided by Conceiveplease

About the Founder, Dr Raewyn Teirney 

“I am one of only a handful of female Fertility Specialists and Gynaecologists in Sydney. I have been in medical practice for over 20 years and have been helping couples with infertility problems for the past 16 years. It is my passion to be the best IVF doctor and IVF specialist in Sydney.
I obtained my MB ChB medical degree from Auckland University, and my Obstetrics and Gynecology training and FRANZCOG degree (Fellowship of the Royal Australian & New Zealand College of Obstetricians & Gynaecologists) in Sydney Australia. My passion for assisting women and couples with their fertility and infertility problems led me to complete further subspecialty training in Reproductive Endocrinology and Infertility. I obtained my CREI- Certification in Reproductive Endocrinology and Infertility from the Royal Australian and New Zealand college of Obstetricians and Gynecologists. During this time I worked as a clinical lecturer at Cambridge University England, and the famous IVF fertility centre, Bourn Hall, where the first IVF baby was conceived.

I now work with IVF Australia and together we provide the highest standards of fertility care available. I have at my finger tips the latest technology and treatments available in Australia to help you achieve your dream pregnancy.”
– Dr Raewyn Teirney 

The Conceiveplease Fertility Kit

Developed by Fertility Specialist and Gynaecologist Dr Raewyn Teirney (MBChB, FRANZCOG, CREI), the conceiveplease™ fertility kit is the first of its kind in Australia, designed to help optimise fertility health and conception. The complete all in one fertility kit has the necessary products needed with easy to follow instructions to help assist couples to conceive naturally. Containing his and hers fertility supplements, medical devices to track and pin point ovulation, fertility calendar to track changes for timed intercourse and pregnancy tests to detect an early pregnancy.
Becoming pregnant is often not straightforward. It is estimated about 1 in 6 couples suffer from difficulty in conceiving. ( Fertility Society of Australia 2004). There are a myriad of causes for not falling pregnant quickly, but a simple factor that is easily corrected is ensuring that sexual intercourse occurs during the fertile window. Conception is most likely to occur when intercourse takes place on the day before or day of ovulation.
The fertility kit is a four-step plan with the above supporting products

Step 1:

Is helping couples get into the best health for fertility by providing evidence based fertility information and providing the male and female preconception vitamins

Step 2:

helps women to track and monitor the menstrual cycle with two types of medical devices to calculate the LH surge and ovulation days, when they are most fertile, and to time sexual intercourse.

Step 3:

is explanatory with timed intercourse around ovulation

Step 4:

the final step of testing for an early pregnancy.
The fertility kit provides two HCG pregnancy tests for this with instructions of use. The four steps seen below have been based on current medical evidence and clinical knowledge. The fertility information in the Conceiveplease™ kit also aims to educate people about the importance of pre-conception health and well-being, and provide steps to for improvement, to help optimise chances of conceiving. Studies show that certain lifestyle factors such as a person’s weight, eating patterns, smoking, alcohol consumption, exercise and sleep have a negative impact on fertility and an ongoing pregnancy.

Conceiveplease™ Preconception & Pregnancy Vitamins

In the antenatal period and during pregnancy women have higher requirements for nutrients to help with the increasing needs of their growing baby. Conceiveplease™ (Australian made) pre-conception and pregnancy vitamins are a formula of 18 essential nutrients to optimise fertility and support a woman during their pre-conception and pregnancy.

Active Ingredients Per Tablet

 

 

 

Vitamin B1(Thiamine Nitrate)

1.6mg

Folic Acid

500mcg

Vitamin B2 (Riboflavine)

1.8mg

Iodine (as Potassium Iodide)

250mcg

Nicotinamide

20mg

Calcium (as calcium Carbonate)

125mg

Calcium Pantothenate

10mg

Iron (as Ferrous Fumarate)

24mg

Vitamin B6(Pyridoxine Hydrochoride)

2.6mg

Magnesium & Phosphorus (as magnesium phosphorus)

125 mg

Vitamin B12 (Cyanocobalamin)

4mcg

Copper (as Cupric Sulfate Anhydrous)

1 mg

Vitamin C (Ascobic acid)

200mg

Manganese (as Manganese Sulfate Monohydrate

1.8 mg

Vitamin D (Cholecalciferol)

500IU

Zinc (as Zinc oxide)

8 mg

Vitamin E(d-alpha-Tocopheryl Acid Succinate)

15mg

Biotin

200mcg

Iron supplementation

Important for reducing anaemia in pregnancy. WHO recommend iron supplementation. The conceiveplease™ pregnancy vitamins contain both iron and the vitamin B group to help prevent iron deficiencies during pregnancy.

Folic acid

Important because requirements are increased in pregnancy because of the rapidly dividing cells in the fetus. It is especially needed in the preconception period to help close the neural tube during the first 4 weeks of fetal development to prevent neural tube defects like spina bifida. This is often the time when women do not know they may be pregnant. Commencing a daily intake of folic acid (400mcg) and iron(30mg) is a recommendation from the World Health organisation, governments and Doctors.
The WHO recommend “oral iron and folic acid supplementation as part of the antenatal care to reduce the risk of low birth weight, maternal anaemia and iron deficiency”. WHO Guideline library: Daily iron and folic acid supplementation in pregnant women.

Iodine

An essential nutrient needed for normal development of the brain and nervous system in the developing baby. The WHO and the NHMRC recommends pregnant women top up their iodine intake by taking oral iodine 250 mcg as a supplement. Women should start from the point of planning a pregnancy through the full duration of pregnancy and breastfeeding.

Vitamin D and Calcium

Important for bone health. During pregnancy extra vitamin D and calcium is required for fetal skeletal bone growth. Keeping levels of vitamin D high is also important for obstetric outcomes with a reduction in low birth weight babies, reduction in pre-eclampsia and preterm birth.

Vitamin C

Vitamin C requirements increase in pregnancy as it is actively transported across the placenta. Vitamin C also promotes the absorption of iron in the gut and helps in preventing anaemia. The NHMRC recommended dose is 70mg per day. The conceiveplease vitamin C dose is higher at 200mcg to also act as an anti-oxidant to remove free radicals formed from oxidative stress.

Zinc and Vitamin C

The conceiveplease™ formula contains the Antioxidants Zinc which with vitamin C may help with immunity in fighting infections.

Micronutrients

Micronutrients are vitamins and minerals required in minute amounts for normal functioning, growth and development. They play an important role in pregnancy and birth outcomes. These include magnesium, copper, zinc, manganese. Nine trials ( involving 15,378 women) showed micronutrient supplementation helped reduce the number of low birth weight babies, and reduced maternal anaemia. (Haider BA, Bhutta ZA Multiple -micronutrient supplementation for women during pregnancy. The Cochrane Collaboration, Issue 1, 2009, 1-35) The aim is to support women in their pre-conception planning and during their pregnancy. These are included in the fertility kit for preconception and pregnancy support but are also sold individually.

References

1. WHO Guideline Library: Daily iron and folic acid supplementation in pregnant women.
2. World Health Secretariat (2007) World Health Organisation Technical Consultation on the Prevention and control iodine deficiency. Public Health Nutrition: 10; 1606-1611
3. National Health and Medical Research Council and New Zealand Ministry of Health (2006) Nutrient Reference Values for Australia and New Zealand including Recommended Dietary Intakes. http://www.nhmrc.gov.au
4. Wilson RD, Johnson JA, Wyatt P et al 2007, ‘Pre-conceptional Vitamin/Folic Acid Supplementation 2007: The Use of Folic Acid in Combination With a Multivitamin Supplement for the Prevention of Neural Tube Defects and Other Congenital Anomalies’, Journal of Obstetrics and Gynaecology Canada, Dec;29(12): 1003-26
5. National Health and Medical Research Council 2010, Iodine supplementation for pregnant and breastfeeding women, National Health and Medical Research Council Public Statement, January, Australia
6. Rumbold A, Crowther CA Vitamin C supplementation in pregnancy. The Cochrane Collaboration library, 2010, Issue 7
7. Haider BA, Bhutta ZA Multiple -micronutrient supplementation for women during pregnancy. The Cochrane Collaboration, Issue 1, 2009, 1-3 8. Grudman M et al. Vitamin D- roles in women’s reproductive health. Reproductive Biology and Endocrinology 2011, 9: 146

Conceiveplease™ Spermplus® for Men Only vitamins

It takes two to conceive and men and the health of their sperm is important for a healthy pregnancy. Conceiveplease™ has developed a daily pre-conception supplement for men called Conceiveplease™ SpermPlus® for Men Only Vitamins. Australian made, each capsule is rich in antioxidants and minerals to support healthy male fertility and sperm health by fighting off free radicals. It also contains high dose selenium for helping testosterone production and vitamin D which is positively associated with sperm motility. Our formula is based on evidence from published medical studies of antioxidant therapy use in men.

Active Ingredients

Label Claim per tablet

Vitamin C- ascorbic acid

125 mg

Zinc (from zinc oxide)

30 mg

Natural vitamin E (d- alpha-Tocopherol)

400 IU

Folic acid

500mcg

Lycopene                    

5mg

Garlic oil

330mg

Selenium (from Selenomethionine) 

75mg

CHOLECALCIFEROL (Vitamin D3)

500IU

CALCIUM ( as Carbonate)

125mg

Sperm and their DNA

Based on multiple clinical sperm studies, it is known that sperm and their DNA are vulnerable to damage by a process called oxidative stress. This occurs when there is an excess production of molecules called reactive oxygen species (ROS), also known as free radicals. It is thought that the ROS damages the sperm membrane, and reduces the sperm’s movement and its ability to bind to the egg, thus blocking fertilisation. The ROS can also have a direct effect on the DNA within the sperm, causing the DNA to fragment. DNA fragmentation signifies that some of the strands of DNA have been broken. If these breakages are not serious, then they can be repaired in the female egg after fertilisation. However, above a certain percentage of breakage, the DNA repair process is not possible at a sufficient level to allow the embryo to develop in a normal fashion.

Exposure to poor lifestyle factors such as smoking, poor diet, alcohol and environmental factors such as medications, toxins and testes exposed to heat is known to increase the production of these free radical. In other words, a man’s lifestyle can affect his sperm. Starting a daily supplement containing antioxidants can promote sperm health.

Antioxidants

Micronutrients that behave like scavengers and protect the body against damage by removing the free radicals before they cause harm to sperm and its DNA. A large review of 34 studies involving 2876 men showed that men who used a daily antioxidant supplement had improved sperm counts and motility and a statistically significant increase in live births when compared to those not on oral antioxidants, adding to the growing evidence that they help to reduce stress and protect sperm. Antioxidants and minerals that help support sperm health include vitamins C, vitamin E, beta-carotene, selenium, lycopene, folic acid, zinc and garlic. (Showell MG, Brown J et al. 2011, ‘Anti-oxidants for male subfertility’, Cochrane Database of Systematic Reviews Vol 19 no 1)

Selenium

Selenium is required for testosterone synthesis and normal sperm maturation and motility. Our SpermPlus® vitamin formula contains a high dose of 75 mg of selenium per capsule. Vitamin D: In men vitamin D is important for testosterone production, libido and sperm production. The receptor for vitamin D is on the acrosomal head of the human sperm. large studies from the University of Copenhagen Denmark showed men with lower blood levels of vitamin D had reduced testosterone and reduced sperm quality while men with higher levels had higher testosterone and higher sperm motility. (Blomberg JM et al. 2011, ‘Vitamin D is positively associated with sperm motility and increases intracellular calcium in human spermatozoa’, Human Reproduction Vol 26 no 6, p.1307-1317)( Lerchbaum E, Obermayer-Pietsch B 2012, ‘Vitamin D and Fertility: a systematic review’, European Journal of Endocrinology Vol 166 no 5, p.765-778)

The aim is to support men in the pre-conception planning period. Because sperm take 72 days to be made our SpermPlus® anti-oxidant formula should be started early and continued until a pregnancy is confirmed. These are included in the fertility kit for preconception and pregnancy support but are also sold individually.

References

1. Sharma R, Beidenharn KR et al. 2013, ‘Lifestyle factors and reproductive health: taking control of your fertility’, Reproductive Biology and Endocrinology Vol 11 no 66
2. Jensen TK, Andersson AM, Jørgensen N et al. 2004, ‘Body mass index in relation to semen quality and reproductive hormones among 1,558 Danish men’, Fertil Steril Vol 82 no 4, p.863-870
3. Hammoud AO, Wilde N, Gibson M et al. 2008, ‘Male obesity and alteration in sperm parameters’, Fertil Steril Vol 90 no 6, p.2222-2225
4. Sallmén M, Sandler DP et al. 2006, ‘Reduced fertility among overweight and obese men’, Epidemiology Vol 17 no 5, p.520-523
5. Mendiola J, Torres-Cantero AM et al. 2010, ‘A low intake of antioxidant nutrients is associated with poor semen quality in patients attending fertility clinics’, Fertil Steril Vol 93 no 4, p.1128-1133
6. Silver EW 2005, ‘Effect of antioxidant intake on sperm chromatin stability in healthy nonsmoking men’, International Journal of Andrology Vol 26 no 4, p.550-1336
7. Wogatzky J, Wirleitner B et al. 2012, ‘The combination matters – distinct impact of lifestyle factors on sperm quality: a study on semen analysis of 1683 patients according to MSOME criteria’, Reproductive Biology and Endocrinology Vol 10 no 115
8. Blomberg JM et al. 2011, ‘Vitamin D is positively associated with sperm motility and increases intracellular calcium in human spermatozoa’, Human Reproduction Vol 26 no 6, p.1307-1317
9. Lerchbaum E, Obermayer-Pietsch B 2012, ‘Vitamin D and Fertility: a systematic review’, European Journal of Endocrinology Vol 166 no 5, p.765-778
10. Showell MG, Brown J et al. 2011, ‘Anti-oxidants for male subfertility’, Cochrane Database of Systematic Reviews Vol 19 no 1